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Are there any long-term side effects of Wegovy (semaglutide)

By week 12, the appetite suppression reaches a stable plateau, meaning further dose increases produce diminishing appetite returns, though they may enhance other metabolic benefits

The mechanisms by which incretin-based therapies exert these effects include signals in the central nervous system to suppress appetite, increase satiety, and thereby decrease calorie intake, improvements in insulin sensitivity, and many other extrahepatic effects [91]

The S-glutathionylation is a process in which the interaction between GSSG and cysteinyl residues of proteins results in the formation of mixed disulfides (22)