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Pregnant individuals or those planning pregnancy should discuss the potential risks and benefits with their healthcare provider to determine appropriate treatment options

H.et al (2023)

Interestingly, in pancreatic ductal adenocarcinoma (PDAC), uncoupling protein 2 (UCP2) can transport the aspartate derived from glutamine metabolism from mitochondria to the cytoplasm to generate NADPH, and silencing UCP2 can significantly inhibit the growth of PDAC

Initially developed for managing type 2 diabetes, Wegovy is approved for weight management and has demonstrated significant effectiveness in clinical trials