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570,571 For example, based on the unique mechanism of action of ASOs, the main safety issues are severe hepatotoxicity and nephrotoxicity caused by drug accumulation

Compounded semaglutide is not FDA-approved, and its safety and effectiveness have not been established

In the Q&A, he added that "a lot of patients on compounded products will go to branded products" enabled by Novo's channels and collaborations, while President and CEO Lars Fruergaard Jrgensen said it was the "right moment" to make a serious change in the market and that this was "baked into" second-half guidance

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