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Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat
Accelerated gastric emptying, which can occur after sleeve gastrectomy, may allow less time for B12 extraction and binding, though this is considered a secondary mechanism
As a consequence, one's kidneys are no longer able to reabsorb as much water as they should be absorbing, therefore creating excessive volumes of urine and the subsequent overall dehydration
NOS1 catalyzes the production of nitric oxide (NO), a crucial neurotransmitter involved in brain development, synaptic plasticity, learning, and memory processes [78, 79]
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