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Site Irritation Because DES is injected intramuscularly into the trained muscle, injection site soreness or redness can occurespecially with repeated use in the same muscle group

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A detailed thyroid history is essential, including diagnosis date, current levothyroxine dosage, recent TSH and free T4 levels, presence of thyroid nodules, history of thyroid surgery or radioactive iodine treatment, and any family history of thyroid cancer or MEN 2 syndrome