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"This concept could reshape how GLP-1RAs are prescribed across different disease states." The field is evolving in four directions at once: oral formulations, multi-agonist combinations, muscle preservation strategies, and expansion into disease areas beyond metabolic medicine
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Based on existing guidelines and evidence, all individuals who would benefit from obesity treatment, including those prescribed GLP-1s, should be offered or referred for intensive, multicomponent behavioral interventions for both weight reduction and weight maintenance [97]
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