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Since the database had a few missing values (due to missing lab or behavioral data), the regression analyses were conducted in two slightly different ways which generally yielded very similar results: 1) eliminate all participants with missing data for any of the variables in the model at the beginning of the analysis, and 2) eliminate participants on an as-needed basis (i.e., only where there is missing data for any variable in the current step in the analysis)

Consult your doctor before use if you are pregnant, breastfeeding, or taking any antidepressant or sedative medication

In the original 2015 Cell Metabolism paper, MOTS-c activated AMPK, improved insulin sensitivity in diet-induced obese mice, and reduced age-related insulin resistance in older animals [2]

Thyroid conditions, including hypothyroidism, hyperthyroidism, and thyroid cancer, are common