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Thus, corneal ulcer healing (opposed neovascularization, maintained transparency) [76] accords with the beneficial promoting effects (angiogenesis) in other tissues (i.e., tendon, muscle) [80,81,82,83,84,85,86,87,88,89,90,91] and beneficial counteraction (pathologic angiogenesis) in other tissues (i.e., liver) [118]

Among them, the MC3181 derivative was recently found to be extremely efficient in blocking cancer growth and metastasis in a xenograft mouse model of vemurafenib resistant melanoma (Fig

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