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The peptide is typically supplied in lyophilized (freeze-dried) powder form and requires reconstitution with bacteriostatic water before injection
Here are some general guidelines: Mild deficiency: The typical treatment is a 250-500 mcg liquid B12 dose prescribed to patients with the mildest B12 deficiency
Predrag Sikirics group (School of Medicine, University of Zagreb, 1991 ) Most common experimental dose in animal studies: 10 g/kg intraperitoneally or per os, daily Standard targeted pathways: VEGFR2 angiogenesis, NO synthase , 5-HT2A serotonin receptor, dopamine D2 receptor Clinical program in Croatia halted at Phase 2 (Crohns disease) WADA Prohibited List: added in 2022 to category S0 (Non-Approved Substances) Reference sources (PubMed) Sikiric P
It also noted that as B12 deficiency increased, so too did insulin resistance
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