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qPCR was performed on an Applied Biosystems QuantStudio 6 Pro Real-Time PCR System, using TaqMan probes (ThermoFisher Scientific) specific for GRN (Hs00963707_g1) and for PPIA (endogenous reference, Hs99999904_m1)

(2022), the dry method is usually employed on an industrial scale but necessitates purification before consumption due to variations in copra quality and potential harmful compounds

There is some evidence suggesting that ibogaine carries serious safety risks, particularly a dangerous irregular heart rhythm known as arrhythmias which can be fatal, along with neurologic and gastrointestinal side effects