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Cagrilintide side effects Most common (GI-focused): Why GI effects are prominent: Very strong gastric emptying delay Stomach stays full longer Slowed GI transit overall Adaptation occurs over weeks Management strategies: Small frequent meals (5-6 daily) Avoid fatty/greasy foods Ginger supplementation Prescription anti-nausea (Zofran) Fiber and hydration for constipation Protein shakes if can't eat solid food Serious but rare: Pancreatitis ( 20% weight loss (approaching surgery) Side effects higher but manageable Most participants tolerated full doses See our cagrilintide and semaglutide combination guide and cagrisema dosing protocols