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GLP-1 Gut Side Effects: Why Bloating and Constipation Happen and What May Help GLP-1 medications like semaglutide and tirzepatide, sold under brand names such as Ozempic, Wegovy, and Mounjaro, have quickly become some of the most widely used tools for weight loss and blood sugar management, and for many people the results are meaningful

Additionally, treatment retention is a critical aspect, with dropout rates varying significantly based on the type of programranging from 20-70% for inpatient programs and 23-50% for outpatient programs

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The mechanisms gut dysbiosis, immune dysregulation, endothelial damage, mitochondrial dysfunction are well-characterised