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Metabolites such as lactate not only may play a crucial role in immune modulation but also may contribute to central sensitization by altering the synaptic microenvironment (146), thereby potentially establishing a direct link between peripheral metabolic dysfunction and central nervous system inflammation

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That system can go down to a target glucose of 81 mg/dL

Reducing Glucagon Secretion: GLP-1 inhibits the secretion of glucagon, a hormone that increases blood sugar levels by promoting the release of glucose from the liver