In contrast to earlier GLP-1 receptor agonists, which primarily target appetite suppression and glycemic improvement, GLP-3 leverages GCG receptor activation to stimulate lipolysis and elevate basal metabolic rate, thereby contributing to a more pronounced and sustained reduction in adiposity as observed in research models
Most patients experience transient gastrointestinal effects including mild nausea, vomiting, or constipation during initial weeks, which typically resolve as the body adjusts
349,350,351,352 Although cargo uploading exogenously is simple and convenient to operate, the integrity of exosomes may be damaged during the loading process, which may affect the effect and require additional purification steps to remove the unloaded drugs
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