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Long-term maintenance of weight loss and outcomes following discontinuation of retatrutide have not yet been established

That triple action appears to reduce the number of people who simply do not respond

According to Rubino, clinical trials are now being planned to assess whether higher doses of GLP-1 drugs can be used in the acute phase to help patients lose weight, followed by lower "maintenance" doses, which come with fewer side effects and can be prescribed on a long-term basis