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Diagnosis is confirmed through blood tests showing elevated thyroid-stimulating hormone (TSH) and reduced free T4

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After giving long-term reared ovariectomy (OVX) mice with different gradient protein concentrations (standard, low protein, high protein) diet, it was concluded that a large number of lipid droplets were visible in the model group of hepatocytes hematoxylin and eosin (HE) staining and oil red O staining compared with the control group mice