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doi: 10.1016/S0140-6736(00)03238-4 34 JiangZAkeyJMShiJXiongMWangYShenYet al

For supplemental injection training, visit our Patient Video Injection Support Page DUPIXENT is a clear to slightly opalescent, colorless to pale yellow solution available as: Injection: 300 mg/2 mL in a single-dose, pre-filled pen with hidden needle or syringe with needle shield Injection: 200 mg/1.14 mL in a single-dose, pre-filled pen with hidden needle or syringe with needle shield DUPIXENT is available in cartons containing 2 pre-filled pens or syringes with needle shields

This controlled inflammation leads to: Increased fibroblast activity Enhanced collagen deposition Strengthening of the weakened ligaments Improved joint stability and function Unlike steroid injections, which suppress inflammation and may degrade tissue over time, prolotherapy seeks to stimulate tissue regeneration

DSIP also shows effects on stress-induced emotional and psychological responses