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Additionally, the following may produce brain fog: Oxygenation problems due to lung or cardiac issues Inflammation in multiple systems Medication side effects Sleep disturbance Stress, anxiety, and social isolation Under investigation: role of the hypothalamus filtering waste in the brain (microglia/CSF) Other Disease Processes Fibromyalgia Myalgic encephalomyelitis Lupus Traumatic Brain Injury (TBI) Orthostatic intolerance and other cerebral blood flow issues Iatrogenic causes (i.e., treatments creating symptoms: chemotherapy, medication side effects, restricted diets for weight loss) NOTE: please discuss any concerns with your doctor and do not discontinue recommended treatments although some treatments may cause adverse side effects, they are life saving and may have the potential to improve cognitive functioning (for example, when an obese person loses weight) As you can see, many conditions and factors can cause or contribute to brain fog

I treat it as a tool with a strong mechanistic rationale, an excellent safety signal in the studies we have, and a body of evidence that's still maturing on the human side

Contraindications QSYMIA is contraindicated in patients: Who are pregnant [see Warnings and Precautions (5.1) and Use in Specific Populations (8.1)] With glaucoma [see Warnings and Precautions (5.3)] With hyperthyroidism Taking or within 14 days of stopping a monoamine oxidase inhibitors [see Drug Interactions (7)] With known hypersensitivity to phentermine, topiramate or any of the excipients in QSYMIA, or idiosyncrasy to the sympathomimetic amines