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Our study highlights several biological pathways by which GLP1 drugs may influence Alzheimers, including reducing inflammation, improving insulin signaling in the brain, and altering enzymes involved in the production of beta-amyloid. Diabetes is a well-known risk factor for dementia, in part because high blood sugar levels can damage blood vessels throughout the body, including in the brain

Moreover, fat mass in rats on the fcHFHS diet was significantly higher compared to rats on the fcHS and fcHF diets [ F (3,20) = 13,65