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During monotherapy evaluation of epilepsy in pediatric patients 6 to 15 years of age, the following effects occurred in patients receiving topiramate 50 mg per day vs

The presence of translation-inhibiting secondary structures within the 5 UTR of mRNA transcripts has been previously demonstrated [82, 86], and designing ASOs that are complementary to these regions, could potentially relieve translational inhibition (Fig

NbGSTU4 binds to the 3 untranslated region (UTR) of BaMV positive sense (+) RNA in a GSH-dependent manner and is necessary for efficient viral RNA replication i.e., production of a viral negative sense () RNA and then new genomic (+) RNA (Chen et al., 2013)