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Several studies have investigated the potential of polyphenols to inhibit NOX activity and reduce ROS production, and it has been observed that these natural compounds prevent NOX expression [90]

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The side effects that do exist are narrow and well-characterized: gastrointestinal upset at higher oral doses, a distinctive fishy body odor from a carnitine metabolite, and one genuinely debated caveat an indirect cardiovascular signal involving the gut-derived metabolite TMAO