on semaglutide and constipation Managing While Using Tirzepatide Semaglutide (Ozempic and Wegovy) Constipation:

doi:10.1111/jdv.20197

Clinical safety guidance suggests that semaglutide may still be safe if: Exposure was brief Temperature limits were not exceeded The medication shows no visible changes However, pharmaceutical safety standards recommend discarding biologic medications if storage conditions are uncertain, as visual inspection alone cannot confirm potency

PMID 18439257

This dual action allows for appetite regulation without compromising postprandial digestion and absorption, minimizing gastrointestinal discomfort such as bloating and nausea, and aligning well with the needs of patients with gastrointestinal dysfunction