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The Vegan Society website states: To get the full benefit of a vegan diet, vegans should do one of the following: eat fortified foods two or three times a day to get at least three micrograms (mcg or g) of B12 a day, OR take one B12 supplement daily providing at least 10 micrograms, OR take a weekly B12 supplement providing at least 2000 micrograms

MOTS-C is mitochondria-encoded, not nuclear-encoded - an entirely unique mechanism not shared by any other known peptide in current research literature

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