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Much evidence has accumulated over the past decade suggesting that patients infected with such RNA viruses are under chronic oxidative stress [8] associated with glutathione depletion because oxidative stress, and the associated overproduction of reactive oxygen species, is a hallmark of RNA viruses

doi:10.1002/ptr.3294

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Lower levels of GSH were also observed in the substantia nigra of PD patients and the caudate nucleus of progressive supranuclear palsy (PSP) patients 16