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Since HNMT (the intracellular histamine-degrading enzyme) requires SAMe, impaired methylation can slow histamine clearance, especially in tissues like the brain and airways, where HNMT is the primary clearance pathway

The prevalence and burden of CD remain high because of the lack of understanding of the etiology, medical assessment, and management (Raghunath et al., 2022)

In amphetamine-induced stereotypy models (a pre-clinical model of schizophrenia-like conditions), DSIP normalised brain metabolism and MAO activity disrupted by long-term amphetamine treatment, establishing a role for adrenergic system normalisation as a mechanism of DSIPs neuroprotective activity

This hydrating fluid does double duty: it carries nutrients throughout your system while helping your kidneys flush out toxins more efficiently