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25 In Gram-negative bacteria, the loss or mutation of porin proteins restricts the entry of hydrophilic drugs

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In the following sections of the manuscript, we emphasize the role of immunologic disturbances associated with G6PD deficiency, such as neutrophil dysfunction, impaired inflammasome activation, and disruption in the NF-B signaling pathway, which may contribute to increased ROS production, viral replication, and contagiousness in SARS-CoV-2 infection