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In patients with T2DM who are poorly controlled by metformin, increasing DUL from 1.5mg to 3.0mg or 4.5mg can provide glycosylated hemoglobin and weight loss related to clinically relevant doses and has similar safety (111)

Piazza explains further why he recommends using these three supplements to all his surgical patients: Post-Surgery Supplement Protocol When to Resume Taking Supplements After Surgery While its important to follow your surgeons instructions on the day of your procedure, it's perfectly fine to pause these supplements for the day of surgery