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In an in vitro study, excitotoxicity was induced in cultured cortical neurons with glutamate, N-methyl-D-aspartate (NMDA), and kainic acid (KA) to produce 50% cytotoxicity

Across reviews and meta-analyses, benefits when they appear tend to emerge at gram-level intakes used in human studies, not at the tens or hundreds of milligrams sometimes seen in general supplements.12 15 When DCI is included, its usually provided in much smaller amounts, often alongside MI

Side effects are rare but may include nausea, mild headaches, or allergic reactions in some individuals

Specifically, it was shown that Hexarelin promotes neurogenesis in the dentate gyrus and subgranular zone of the hippocampus, which is responsible for storing existing memories and creating new memories