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In addition, we focused on glucagon, a known polypeptide that regulates glucose levels and a classic molecule that induces autophagy

In addition, current evidence gaps exist due to lack of research stan-dardization in examining symptom clusters, incomplete research on herbal toxicity and safety, insufficient evidence for direct antitumor activity of herbs (relying mostly on pre-clinical data), few high-quality RCTs to validate their clinical efficacy, and studies in homogeneous populations (Asian) lacking generalizability [58]

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