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Low urinary pH predisposes for uric acid precipitation since the pKa of uric acid is 5.7, therefore the solubility of uric acid decreases with low pH, and thus increasing the risk of kidney stones ( Hypercalciuria has also been documented following keto-induction, with some studies documenting a 60% increase in excreted calcium, which could increase the risk of precipitation and developing kidney stones (73)

Most therapeutic peptides are drugs, most of the popular ones are unauthorized, and selling or importing them is illegal

The mitochondrial-derived peptide MOTS-c relieves hyperglycemia and insulin resistance in gestational diabetes mellitus

While they use the same active ingredient, equivalence to FDA-approved finished products should not be assumed