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Cabaguio Ave., Davao City, 8000, Philippines Corresponding Author: Robert Keller, 16259 Laguna Canyon Road, Irvine, CA 92618, USA, Phone +1 619 675-4103, Fax +1 619 684-3152, Email: robert@ nutraclinicalinc.com Abstract Aim: To evaluate the effect of purple Mangosteen fruit pulp powder (MX3) on subjects with knee joint discomfort and reduced joint function