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J Biol Chem (1987) 262:897580

Your provider might adjust your dose based on your vitamin B12 levels, whether you have medical conditions that cause lower vitamin B12 levels (e.g., Crohn's disease), or whether you're taking other medications that affect vitamin B12 levels.

The Endocrine Society's 2020 position statement on peptide therapeutics emphasizes that "the absence of Phase I dose-escalation data for novel peptides like BPC-157 means that any dose recommendation is extrapolated, not validated, and clinicians should err on the side of the lowest effective dose" 19

Cagrilintide showed a higher rate of injection site reactions compared to placebo, including mild redness and irritation