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Given the superior hydro-phobicity of quercetin (LogP = 1.8) compared to carnosine (LogP = -3), quercetin was selected for labeling with FITC

TPO is a key enzyme in the synthesis of thyroid hormone responsible for catalytic oxidation of iodine and iodization of tyrosine, and inhibition of TPO activity can directly lead to reduced thyroid hormone synthesis (Godlewska and Banga, 2019)

It shifts the cellular environment from a state of toxic stagnation back toward functional energy metabolism

Studies in non-human models show significant effects on adipose tissue regulation, nutrient absorption kinetics and glucose homeostasis, making this combination a valuable tool for analysing complex metabolic interactions