In the STEP and SURMOUNT trials: Constipation was reported in up to 24% of patients on semaglutide 18-23% of patients on tirzepatide experienced constipation It is one of the top three side effects of these medications and is more frequent in those who: Lose weight rapidly Eat low-fiber diets Are female (due to hormonal factors affecting gut motility) Conventional Treatment Approaches Most providers recommend over-the-counter (OTC) remedies such as: Stool softeners (docusate) Fiber supplements (psyllium, methylcellulose) Laxatives (PEG 3350, senna, Mag Citrate) These can help in the short term but do not address the root cause
Maintain a diet rich in lean proteins, whole grains, and fresh fruits and vegetables to support energy metabolism
We are now at an inflection point for The Broadening of GLP-1 use, which will extend beyond US-based early adopters to date, to larger numbers of patients globally, Morgan Stanley analysts wrote this year
Instead, CMS will use a single central processor for administrative functions, including prior authorization, claims adjudication, and pharmacy payment