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Dosing began at 0.25 mg of each active drug and escalated every four weeks until the full 2.4 mg dose was reached by week 16

Crit Rev Biochem Mol Biol 30:521600

In our study, melatonin-treated ILC2s exhibited increased intracellular NRF2 staining, consistent with enhanced availability of active NRF2

MATERIALS AND METHODS Formalin-induced nociceptive behavioral test The time-effect curves of the control, morphine, and BPC-157 (from 10 to 40 g/kg) groups for the flinching response in the formalin test are shown in Figure 1