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A study published in the Annals of Internal Medicine examined GHRH analog administration in older adults and found significant reductions in visceral fat, increases in lean body mass, and improvements in physical performance markers over 6 months

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Various GLP-1RAs have been demonstrated to have significant benefits in in vitro and in vivo models of neurodegenerative diseases through modulating a variety of pathogenic mechanisms, including neuroinflammation, autophagy, mitochondrial dysfunction, and the abnormal phosphorylation of pathognomonic proteins