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At the time of this writing, liraglutide is the only GLP-1 RA with a labeled indication to reduce the risk of major adverse cardiovascular events (MACE), yet several other GLP-1 RAs have shown significant reduction in MACE, as summarized in Table 2

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It is commonly prescribed under brand names such as: Ozempic (for type 2 diabetes) Wegovy (for chronic weight management) While clinically effective for many patients, semaglutide has been associated in lawsuits with severe gastrointestinal and systemic complications that may require long-term treatment or hospitalization

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