semaglutide and dry skin Weekly injections helped me lose 25+/- since September 2025. , No negative side effects that you typically hear about. The only thing uncomfortable that I am experiencing is extremely Dermatologist Explains Ozempic Face, Hair

doi: 10.1093/hmg/ddu542

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Because whilst the potential pain benefits are interesting, there are specific reasons why the hypermobility and Ehlers-Danlos population needs to approach GLP-1 drugs with considerably more caution than the general public

GLP-1 stimulation in the microbiome Human intestinal cells show Akkermansias effect on GLP-1 production Akkermansia secretes p9 protein which stimulates GLP-1 production Clostridium butyricum increases GLP-1* Dose-dependent increase of GLP-1 by Clostridium butyricum in a cell-based assay *Based on internal Pendulum R&D data Breakthrough clinical research Were continually pushing the boundaries in scientific research, and were excited to conduct a human clinical trial on GLP-1 and the gut microbiome