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Due to their numerous advantages, both vaginal inserts and suppositories have been widely prepared in pharmacies since the 18 th century to achieve both systemic and local effects

Analytical guidance such as ICH Q2(R2) and ICH Q14 supports the broader principle that methods should be fit for purpose and properly documented [13] [14]

Objective In this narrative overview, the following selection criteria were used: Inclusion criteria included (a) journal reports and/or reviews of clinical studies using pre-, peri-, or postmenopausal women in combination(s) with collagen, hyaluronic acid, curcumin, glutathione, and estrogen deficiency and (b) articles from 2020 to 2025

Research is ongoing, and more human studies are needed to better understand BPC-157's potential role in supporting immune health