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Results of the Dapagliflozin and Prevention of Adverse Outcomes in Chronic Kidney Disease (DAPA-CKD) trial, which compared dapagliflozin (10 mg once daily) to placebo, found that dapagliflozin was associated with a 44% reduction in a composite of adverse kidney outcomes and a 29% reduction in death from cardiovascular causes or hospitalization for heart failure

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Here, we will review how T cell metabolism influences the development of inflammation in the synovial tissue, focusing on three major metabolic pathways: glucose metabolism, glutamine metabolism and lipid metabolism