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That combination is why the weight loss numbers look the way they do

Mounjaro is a new once-weekly GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist, and is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes

Key mechanisms underlying this transition include chronic inflammation, lipotoxicity, and immune dysfunction [29, 63]

The most frequent gastrointestinal side effects include: Nausea (very common: may affect more than 1 in 10 people) Diarrhoea (common: may affect up to 1 in 10 people) Constipation (common: may affect up to 1 in 10 people) Vomiting (common: may affect up to 1 in 10 people) Abdominal pain and discomfort (common) Dyspepsia and bloating (common) These symptoms are typically mild to moderate in severity and often improve over time as the body adjusts to the medication