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With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023

Clinically, GACLIV is often incorporated into wellness programs to enhance post-workout recovery, improve fat metabolism and endurance, boost cognitive focus and alertness, and support overall wellness, energy, and vitality

The degradation process follows a predictable pattern