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These are products of metabolism (metabolites) that provide insight into: Digestive and microbiome health (ex: malabsorption, SIBO) Cellular energy production and mitochondrial health Neurotransmitter levels Vitamins that are cofactors to certain enzymes, including B vitamins Toxins and detoxification capacity Amino acids the building blocks of protein Essential amino acids (the ones we need from the diet) Nonessential amino acids (the ones that the body makes from the others) Intermediate metabolites of amino acid metabolism that inform us about B vitamin status, the nitrogen cycle and methylation