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At the end of the study, six of the ten MVD-affected dogs being fed the CNB-laced kibble showed modest improvements in their heart measurements, while one of those dogs progressed to severe mitral regurgitation

Cell 182 , 933946.e14 (2020)

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A further study reported that tenocytes stimulated with IGF-1 (100 ng/mL) for 7 days exhibited a significantly increased cell proliferation compared to the tenocytes in cell groups cultured without IGF-1 ( Overall, these results demonstrated the pivotal role of IGF-1 in enhancing cell proliferation and migration