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If sleep problems develop during use, consider other factors such as stress, caffeine intake, exercise timing, or the psychological effects of any new health regimen

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Proton pump inhibitors (acid blockers) and over-the-counter non-steroidal anti-inflammatory agents can change the environment of the GI tract predisposing to nutrient deficiencies Unfortunately, that isnt an exhaustive list, but it does give you a pretty good idea of why you should be concerned about your vitamin B12 levels

This peripheral inflammation is a known driver of neuroinflammation, which is implicated in mood disorders, cognitive decline, and neurodegenerative diseases