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Therefore, future clinical translation will probably benefit from biomarker-guided frameworks, incorporating (1) FSP1 abundance/localization, (2) CoQ pool size and redox state, (3) lipid peroxidation signatures and (4) metabolic context (mitochondrial activity and sulfur/selenium flux)

Fiber rich legumes, fruits, and whole grain diets provide food for good bacteria

But Lilly, Novo Nordisk, and other companies are developing small-molecule-based pills that are easier and cheaper to manufacture than peptides

However, based on our healthcare teams view of GLP-1 penetration, we think the more likely scenario is a one- to two-percentage-point volume reduction over the course of a decade or more