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When oxidative stress is high, hormone signaling can become imbalanced, and the environment needed for fertilization, implantation, and early pregnancy becomes less stable

Extra weight puts strain on the heart, making exercise more difficult

The overall loss of Complex I subunits is in this respect remarkable and indicates that this part of the respiratory chain is severely affected in lipid storage myopathy associated with sertraline treatment

313 Several therapeutic approaches targeting Met metabolism, including Met restriction, MAT2A inhibitors IDE397 and AG-270, are in clinical trials, and their therapeutic effects need to be verified