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HMB (hydroxy methyl butyrate)A metabolite of the essential amino acid Leucine

Lipolysis is associated with improved metabolic health

It appears to stimulate the expression of growth factors and support the structural repair of axons and myelin sheaths, highlighting its potential as a therapeutic agent for various forms of neuropathy and nerve damage

Study selection The criteria for including studies in this meta-analysis were as follows: (1) (i) randomized controlled trials (RCTs) comparing different AOMs with placebo, including glucagon-like peptide 1 receptor agonist (GLP-1 RA), dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 RAs, GLP-1 and glucagon receptor (GCGR) dual-agonist, orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and bimagrumab