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Erastin triggers ferroptosis in colorectal cancer cells by activating the PERK-NRF2-HO-1 signaling pathway, thereby exerting potent anti-tumor effects ( 3 Ferroptosis and NAFLD 3.1 Ferroptosis and inflammation Globally, the prevalence of NAFLD continues to rise, encompassing a spectrum of conditions from simple steatosis to NASH, fibrosis, and cirrhosis (52), a high-fat diet-induced mouse model was employed to evaluate the effects of ferroptosis inhibitors on NAFLD progression

[7] [8] When body fat decreases rapidly, oestrogen levels may fluctuate, potentially leading to irregular periods, lighter bleeding, or temporary amenorrhoea (absence of menstruation)