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N-Acetylcysteine N-acetylcysteine (NAC) is an antioxidant that scavenges free radicals and supports detoxification capacity

CRP binds and aggregates oxidized low-density lipoprotein (ox-LDL) and enhances macrophage oxLDL uptake, promoting mitogen-activated protein kinase activation (171) required for foam cell formation (172)

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Separation of the digests was achieved by employing a C18 EASY-Spray HPLC column (75 m 500 mm, 2 m, ES903 Thermo Fisher Scientific) with a linear gradient ranging from 4% to 90% acetonitrile at a flow rate of 300 nL per minute (nL/min) over a duration of 150 min